Download
The source code for BioSeq-BLM:
BioSeq-BLM --- The source code on github.
The stand-alone package and manual for BioSeq-BLM:
Version-1.0[created on 2021-8-22]:
BioSeq-BLM.zip --- The source zip file for stand-alone package on Windows and Linux.
Quick Start:
BioSeq-BLM_manual.pdf --- For how to use stand-alone package of BioSeq-BLM.
The tutorial for BioSeq-BLM webserver:
webserver-tutorial.pdf --- You can use the webserver with the guidance of this tutorial step by step.
The datasets used in BioSeq-BLM:
1. Identification DNase I hypersensitive sites
2. Identification of real microRNA precursors
3. Identification of DNA binding proteins
4. Identification of intrinsically disordered regions in proteins
5. RNA-binding protein identification
6. RNA secondary structure prediction
Notes: You can download these datasets to test stand-alone package or webserver.
Supporting Information for the physicochemical indices:
Supporting Information S1-DNA-90.txt
--- The 90 physicochemical indices for dinucleotides(DNA) used in BioSeq-BLM(1-2).
Supporting Information S2-DNA-12.xls
--- The 12 physicochemical indices for trinucleotides(DNA) used in BioSeq-BLM(1).
Supporting Information S3-RNA-11.txt
--- The 11 physicochemical indices for dinucleotides(RNA) used in BioSeq-BLM(1).
Supporting Information S4-aaindex.txt
--- The 547 physicochemical indices for amino acids used in BioSeq-BLM(3).
References:
1.Chen, W., Zhang, X.T., Brooker, J., Lin, H., Zhang, L.Q. and Chou, K.C. (2015) PseKNC-General: a cross-platform package for generating various modes of pseudo nucleotide compositions.Bioinformatics, 31, 119.
2.Friedel, M., Nikolajewa, S., Suhnel, J. and Wilhelm, T. (2009) DiProDB: a database for dinucleotide properties. Nucleic Acids Research, 37, D37-D40.
3.Kawashima, S., Pokarowski, P., Pokarowska, M., Kolinski, A., Katayama, T. and Kanehisa, M. (2008) AAindex: amino acid index database, progress report 2008.Nucleic Acids Research, 36,D202-D205.